產(chǎn)品編號: KMP2237
產(chǎn)品名稱: Rhesus Macaque CD47 Protein, His Tag, Flag Tag
中文名稱: Rhesus Macaque CD47重組蛋白
中文全稱: 重組食蟹獼猴整聯(lián)蛋白相關(guān)蛋白
關(guān)鍵詞: 整聯(lián)蛋白相關(guān)蛋白, Leukocyte Surface Antigen CD47, Antigenic Surface Determinant Protein OA3, Integrin-Associated Protein, IAP, Protein MER6, CD47, MER6, Rhesus Macaque CD47 Protein, His Tag, Flag Tag, Re*binant Protein, KMP2237
物種: Rhesus Macaque
宿主: HEK293 Cells
規(guī)格: 50ug, 100ug, 200ug
純化方式: Affinity purification
純度: >95% as determined by SDS-PAGE
內(nèi)毒素水平: <1.0 EU/ug determined by the LAL method
緩沖體系: PBS, pH7.4
Uniprot: F7A802
產(chǎn)品背景: CD47, also known as Integrin-Associated Protein(IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain(ECD) with a single Ig-like domain, five membrane-spanning regions with short intervening loops, and C-terminal cytoplasmic tail. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important role in memory formation and synaptic plasticity in the hippocampus. As a receptor for SIRPA, it binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cellcell adhesion, it enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. It may play a role in membrane transport and/or integrin dependent signal transduction. It also prevents premature elimination of red blood cells.
保存條件: Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
運輸條件: In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
說明: This product is for research use only.
官網(wǎng)鏈接: https://***.kmdbioscience.cn/