馬兜鈴酸 Aristolochic acid
Reversible non*petitive PLA2 inhibitor.
Phospholipase A2 (PLA2) inhibitor active against the enzymes found in many snake venoms as well as those of human platelets and synovial fluids. Inhibits ionophore-stimulated PLA2 activity in human neutrophils. Has been shown to be nephropathic and carcinogenic.
PRODUCT PROPERTIES
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Alternative Name:
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8-Methoxy-6-nitrophenanthrol(3,4-d)-1,3-dioxide-5-carboxylic acid
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MI:
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14: 786
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RTECS:
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CF3325000
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Source/Host:
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Isolated from Aristolochia clematis.
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Solubility:
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Soluble in DMSO or 100% ethanol.
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Long Term Storage:
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+20°C
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Hazard:
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MAY BE CARCINOGENIC.
MAY BE MUTAGENIC. TOXIC. |
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MW:
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341.3
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CAS:
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313-67-7
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Formula:
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C17H11NO7
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Purity:
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≥97% (~1:1 mixture of aristolochic acids I (A) and II (B))
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Appearance:
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Yellow solid.
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普華仕科技發展有限公司 --Puhuashi Technology Development Co., Ltd
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