腔腸素 Coelenterazine (ultra pure)
Cell viability dye
Colenterazine is useful for monitoring calcium in live cells and tissues, in reporter gene assays, for superoxide anion detection and in drug high-throughput screening applications. Coelenterazine is useful for reconstituting aequorin in cells that have been transfected with apo-aequorin cDNA. The aequorin *plex *prises a 22kDa apoaequorin protein, molecular oxygen and coelenterazine. In the presence of Ca(II), coelenterazine is oxidized to coelenteramide, yielding the release of carbon dioxide and blue light.
PRODUCT PROPERTIES
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Alternative Name:
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2-[(4-Hydroxyphenyl)methyl]-6-(4-hydroxyphenyl)-8-(phenylmethyl)-imidazo [1,2-a] pyrazin-3-(7H)-one
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Solubility:
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Soluble in 100% ethanol.
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Long Term Storage:
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-20°C
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Use/Stability:
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Store at -20°C, under nitrogen. Desiccation re*mended. Protect material from long-term exposure to light; may be exposed to light for short periods of time. This material is unstable in DMSO, DMF, dimethylacetamide and N-methylpyrrolidone. Coelenterazine solution in methanol showed <10% de*position when stored at room temperature in the dark for one month, and <2% de*position when stored at –20°C in the dark, under nitrogen.
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Handling:
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Keep cool and dry.
Protect from light. |
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MW:
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423.5
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CAS:
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55779-48-1
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Purity:
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≥90% (HPLC)
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普華仕科技發(fā)展有限公司 --Puhuashi Technology Development Co., Ltd
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